Remembering the first woman to be awarded a Nobel Prize, the first individual to be awarded two Nobel Prizes and still today the only individual with two Nobel Prizes in two different scientific categories: Marie Skłodowska Curie.
Curie was born #OnThisDay in 1867.
As an economist I was hesitant reading this book. But was pleasantly surprised. For a sweeping & accurate history of economics, from ancient Greece to contemporary times—George Akerlof, Joseph Stiglitz, Amartya Sen, all in less than 250 pages, it turned out to be a page turner.
Every researcher's nightmare: "Your sample size is too small to detect that effect."
This open-access paper in Frontiers in Medicine solves that problem BEFORE you collect data.
"How to calculate sample size in animal and human studies" by Zhang & Hartmann breaks down:
✓ What is statistical power? (and why 0.8 isn't magic) ✓ How to choose effect size
✓ What to do when you have pilot data
✓ What to do when you have NO pilot data
✓ How to account for dropouts
✓ Actual G*Power screenshots with parameters filled in
The paper includes worked examples for:
- Comparing two proportions
- Comparing two means
- Studies with unequal group sizes
- Studies expecting attrition
The hard truth: Most underpowered studies aren't because researchers are careless. They're because sample size calculation is genuinely confusing and rarely taught well.
This paper treats you like an intelligent person who just needs clear explanation and practical examples.
Read it before you write your next ethics application or grant proposal.
Your future self (and your reviewers) will thank you.
🔎 How does deranged adipokine signaling explain HFpEF beyond obesity?
Visceral fat… epicardial fat… pericardial fat — all quietly shaping inflammation, fibrosis & function.
A whole-body story of HFpEF 🫀🚶😮💨
#FunctionNotFailure
Insightful read by Milton Packer in this 🔥JCF Ignite! :
👉 doi.org/10.1016/j.cardfail.2…
I have first hand knowledge that patients in the US are offered LAAC as an alternative to oral AC. For things as mundane as bruising, the potential of a fall and ...gulp...cost of DOAC.
CLOSURE AF says this is wrong. It's always been wrong, but now we know.
#AHA25
I've met tons of researchers who hate stats!
If you're one of these, this book is for you ⤵️
Save (with 𝘤𝘭𝘪𝘱𝘱𝘦.𝘮𝘦) & Repost
The author says it perfectly:
"The most important concepts of statistics can be explained, so that ordinary people can understand it."
— No complex formulas.
— No expensive software needed.
— Just spreadsheets & clear thinking.
The book covers:
— Sample surveys
— Data presentation
— Confidence intervals
— Statistical tests
Written for people who need to collect data.
— Analyze results.
— Present findings.
But don't want to become mathematicians.
Real examples throughout.
— Like the Fitness Club survey with 30 kids.
Shows you exactly how to spot bias.
When to use different tests.
How to avoid common mistakes.
Perfect for public health researchers.
Statistics doesn't have to be scary.
(𝘢𝘵𝘭𝘦𝘢𝘴𝘵 𝘪𝘯 𝘵𝘩𝘦 𝘣𝘦𝘨𝘪𝘯𝘯𝘪𝘯𝘨)
💬 Comment if you'd like a link to download this book!
Presented at #AHA25:
In patients with atrial fibrillation after successful ablation, rivaroxaban therapy did not lead to a significantly lower incidence of a composite of stroke, systemic embolism, or new covert embolic stroke than aspirin therapy. Full OCEAN trial results: nej.md/3LsRJ86@AHAScience
Dr. Barry J. Marshall was convinced that H. pylori bacteria causes stomach ulcers, but no one believed him. Since it was illegal to test his theory on humans, he drank the bacteria himself, developed ulcers, treated them with antibiotics, and went on to win a Nobel Prize.
Evolocumab in Patients without a Previous Myocardial Infarction or Stroke: @NEJM@AHAScience#AHA25
🥸VESALIUS-CV - subtilisin–kexin type 9 (PCSK9) inhibitor evolocumab
😱Summary
👇👇👇
The amazing @CBallantyneMD summarizing the first #LBCT & the importance of #CVprev
We must prioritize CV prevention. I would argue Prevention is sexy and the best area of cardiology. Everything else pales in comparison. Join us!
#AHA25
Tomorrow the trial we are all waiting for at #AHA25 is VESALIUS-CV Trial
#VESALIUSCV is the first trial to test a PCSK9 inhibitor for people who’ve never had a heart attack or stroke: moving lipid therapy deeper into primary prevention
📍top line results already released: in 12,000 high-risk adults without prior MI or stroke, adding Evolocumab (140 mg q2 wks) to optimized lipid-lowering therapy for ~4.5 yrs cut major CV events
#HeartHealth#CVPrev#lipids#PCSK9i
Wow. Huge effect of fish oil on CVD outcomes for patients on hemodialysis!
‼️43% reduction in serious cardiac events
❗Significant reductions in many 2ry end points too
🐟 Standard-ish fish oil (1.6 g EPA/0.8 g DHA)
🌽 Versus corn oil placebo
nejm.org/doi/full/10.1056/NE…
📢#ICNC2026 Call for Abstracts & Cases – Share Your Science!
Act now for the opportunity to present your research & clinical cases at #ICNC2026 – The International Conference on Nuclear Cardiology.☢️🫀@EANM_NucMed
Learn more & submit now👇
bit.ly/43Z4D45