Individualized closed-loop acoustic stimulation suggests an alpha phase-dependence of sound-evoked and induced brain activity measured with electroencephalogram (EEG) recordings. SUMMARY. Healthy adult brains generate alpha oscillations and individual subjects have unique alpha oscillation frequencies, which impacts how they dynamically process, ignore, and attend to sensory information. Our study uses a novel closed-loop technology and individualized approach to play sounds at physiologically distinct peak or trough phases of ongoing alpha oscillations. We find sounds played phase-locked to trough versus peak alpha phases measured with electroencephalography (EEG) elicit distinct brain potentials and changes in alpha oscillations. This study supports the feasibility of using a novel individualized, closed-loop, neuromodulation to investigate and potentially improve abnormal alpha and other oscillation activity associated with multiple neurological disorders. Congratulations to the research team! @tylor_harlow, Samantha Marques, Scott Bressler. eneuro.org/content/early/202…

to end the half‼️

I wrote a review of James Watson's obituary by @CSHL: liorpachter.wordpress.com/20…

Online now: Human cortical dynamics of auditory word form encoding dlvr.it/TP7snV

NYC = the city that never sleeps? I don't think so!!! Here's what happened when we brought Elemind + a lawn chair around NYC. More to come...

A new technique called ‘mind captioning’ generates descriptive sentences of what a person is seeing or picturing in their mind using a read-out of their brain activity, with impressive accuracy. go.nature.com/4nZaZId

Our TPUs are headed to space!  Inspired by our history of moonshots, from quantum computing to autonomous driving, Project Suncatcher is exploring how we could one day build scalable ML compute systems in space, harnessing more of the sun’s power (which emits more power than 100 trillion times humanity’s total electricity production). Like any moonshot, it’s going to require us to solve a lot of complex engineering challenges. Early research shows our Trillium-generation TPUs (our tensor processing units, purpose-built for AI) survived without damage when tested in a particle accelerator to simulate low-earth orbit levels of radiation. However, significant challenges still remain like thermal management and on-orbit system reliability.  More testing and breakthroughs will be needed as we count down to launch two prototype satellites with @planet by early 2027, our next milestone of many. Excited for us to be a part of all the innovation happening in (this) space!

Friends (and friends-of-friends) in LA: Please help spread the word! On Saturday, November 15th 2p, @mameister4 and I will be in conversation at the Burbank Library discussing bottlenecks and next steps for brain research. It's free! Register here: burbank.libnet.info/event/14…

Excited to share what my Paradigms of Intelligence team and I have been exploring for more than a year, a new moonshot from Google: Project Suncatcher. As we work toward one day building ML compute systems in space, there will be many milestones to come - watch this space.

Physicists at the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) in Hamburg have discovered a striking new form of quantum behavior. In star-shaped Kagome crystals—named after a traditional Japanese bamboo-basket woven pattern—electrons that usually act like a noisy crowd suddenly synchronize, forming a collective “song” that evolves with the crystal’s shape. The study, published in Nature, reveals that geometry itself can tune quantum coherence, opening new possibilities to develop materials where form defines function. nanotechnologyworld.org/post…

Aquarium hijinks provide the strongest evidence yet that sharks love to play. Learn more: scim.ag/4o9lEkc @NewsfromScience

The physics of hot water freezing mid air Sometimes called the Mpemba effect

I'm incredibly honored to receive the Bernice Grafstein Award for Outstanding Accomplishments in Mentoring. This makes me very sentimental! I'm so proud of the wonderful, super sharp students and postdocs that I have had the privilege and pleasure to work with. ❤️ Thank you!!!

New preprint out: Incredible work led by Arthur Lefevre showing that marmoset ACC plays a central role in resolving the Cocktail Party when communicating in noisy natural environments. Arthur has started his own lab at CNRS Lyon neuroprime.org biorxiv.org/content/10.1101/…

Here is my new OpED piece about the importance of primate neuroscience research for the future of AI : wsj.com/opinion/the-future-o…

Our piece arguing that all scientists need to engage with the public if we are to turn back the anti-science tide is out in NatNeuro today: rdcu.be/eKV8Y; @MichaelLouisPl1 @aaronbatista KatiGothard, KarenParker, @doristsao @zivwilliamslab

My department,@CornellBME, is hiring! This tenure-track faculty position is a great opportunity to join a vibrant community that values research, teaching, and entrepreneurship. 📝 academicjobsonline.org/ajo/j… @CornellEng @Cornell

Incredibly proud of Lingxiao Shao for receiving the prestigious Peter and Patricia Gruber International Research Award this year! 🎉🎉🎉 A true trailblazer who has been driving research on #psychedelic drug action in the brain. 🧠🧪 @SfNtweets @The_Gruber_Fdtn #SfN2025

This was a fun piece to write for @TrendsinPharma “The ABCs of Psychedelics: A Preclinical Roadmap for Drug Discovery” with @john_mccorvy and @mantschjr cell.com/trends/pharmacologi…

Sleep science reveals that after just 17 hours awake, cognitive performance drops to levels equivalent to a 0.05% blood alcohol concentration. No pill can truly replace the restorative power of natural sleep. 🧠💤 #SleepScience themattwalkerpodcast.buzzspr…

This is one of THE most helpful, brilliant, and comprehensive podcasts on sleep. 🎤-drop 🙌 piped.video/AQF_eopP1ys @michaelgrandner @foundmyfitness