Today, @ekindogus and I are excited to introduce @periodiclabs. Our goal is to create an AI scientist. Science works by conjecturing how the world might be, running experiments, and learning from the results. Intelligence is necessary, but not sufficient. New knowledge is created when ideas are found to be consistent with reality. And so, at Periodic, we are building AI scientists and the autonomous laboratories for them to operate. Until now, scientific AI advances have come from models trained on the internet. But despite its vastness — it’s still finite (estimates are ~10T text tokens where one English word may be 1-2 tokens). And in recent years the best frontier AI models have fully exhausted it. Researchers seek better use of this data, but as any scientist knows: though re-reading a textbook may give new insights, they eventually need to try their idea to see if it holds. Autonomous labs are central to our strategy. They provide huge amounts of high-quality data (each experiment can produce GBs of data!) that exists nowhere else. They generate valuable negative results which are seldom published. But most importantly, they give our AI scientists the tools to act. We’re starting in the physical sciences. Technological progress is limited by our ability to design the physical world. We’re starting here because experiments have high signal-to-noise and are (relatively) fast, physical simulations effectively model many systems, but more broadly, physics is a verifiable environment. AI has progressed fastest in domains with data and verifiable results - for example, in math and code. Here, nature is the RL environment. One of our goals is to discover superconductors that work at higher temperatures than today's materials. Significant advances could help us create next-generation transportation and build power grids with minimal losses. But this is just one example — if we can automate materials design, we have the potential to accelerate Moore’s Law, space travel, and nuclear fusion. We’re also working to deploy our solutions with industry. As an example, we're helping a semiconductor manufacturer that is facing issues with heat dissipation on their chips. We’re training custom agents for their engineers and researchers to make sense of their experimental data in order to iterate faster. Our founding team co-created ChatGPT, DeepMind’s GNoME, OpenAI’s Operator (now Agent), the neural attention mechanism, MatterGen; have scaled autonomous physics labs; and have contributed to some of the most important materials discoveries of the last decade. We’ve come together to scale up and reimagine how science is done. We’re fortunate to be backed by investors who share our vision, including @a16z who led our $300M round, as well as @Felicis, DST Global, NVentures (NVIDIA’s venture capital arm), @Accel and individuals including @JeffBezos , @eladgil , @ericschmidt, and @JeffDean. Their support will help us grow our team, scale our labs, and develop the first generation of AI scientists.

Sep 30, 2025 · 4:00 PM UTC

Congrats on the launch! Doing things in the physical world is underrated by AI people.
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Thanks, John! Yeah, a ton of challenges connecting AI systems end-to-end to physical labs, but we think there's a huge upside in getting it right
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This is the most exciting mission I’ve seen for a new company for a long time
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Thanks, sir! Inspired by your leadership pushing reasoning, and am excited to take it to physical world
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so glad someone is pursuing this! people often underestimate how much work it will take to bring models and bridge them into autonomous real world researchers, so incredibly glad such an excellent team is taking this on.
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Thanks, Will! Huge amount of challenges to do it well, but we're having fun doing the bridge from bits to atoms
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Huge congratulations! As we increasingly master the world of bits, now we can turn our attention to the atoms...
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Thanks, Patrick!
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Congratulations!! I think you are going to be amazingly successful, and I love your company direction.
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Thanks, Jascha! Really appreciate it
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> As an example, we're helping a semiconductor manufacturer that is facing issues with heat dissipation on their chips. geez, unlocking compute potential is just a casual side-quest. way to put all other ai efforts to shame... (congrats on the announcement! can't wait to see what you guys build 🫡)
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Thanks, Susan!!
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Congratulations! Very excited about what you all will bring about!
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Thanks, Igor!
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Congrats Liam! Great to see you and the team pursue this ambitious goal!
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Thanks, Srinivas! Really appreciate it
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This is super exciting. to the age defined by to be discovered new materials. Congratulation, Liam!
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Thanks, Shuchao! Been fun starting our science searches!
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Congrats William, Ekin and team, very exciting!
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Thanks, Thomas!
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Congratulations!! Very exciting!
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Thanks, Azalia!
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Thanks, Rapha!!
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Thanks, Karan!
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Congrats Liam!! Very excited to see how you guys push the frontier 😊
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Thanks, Vivek!
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Congrats!! What a photo too.
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Thanks, Xiao!
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So cool, congrats dude!
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Thanks, Brydon!!
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